Spencer County is a county located in the U.S. state of Indiana. As of the 2010 census, the population was 20,952. The county seat is Rockport. Despite not being in the Owensboro Metropolitan Area, the entire riverfront of the city of Owensboro, Kentucky borders the southern tip of the county.

Area: 401 mi²

Founded: 1818

Population: 19,798 (2021)

County seat: Rockport

Cities: Chrisney, Dale, Gentryville, Grandview, Richland City, Rockport, Santa Claus